Clinical Studies
QUICK LINKS
Frequently Reviewed Documents
QUICK LINKS
Institutional Clinical Studies: Event/Location
CAUTI/UTI: (Catheter Acquired Urinary Tract Infection): Institutional Studies
CLABSI (Central Line Blood Stream Infection): Institutional Studies
Clostridium Difficile (CDI): Institutional Studies
Children’s Hospitals Studies
Alternate Site Studies
QUICK LINKS
Organism, Skin, Alt Site,
Reference Data
Organism Efficacy Studies
Wound and Skin Integrity Studies
Clinical Data Brochure
Reference Documents
Frequently Reviewed Studies

Efficacy of a Novel Skin Antiseptic Against Carbapenem-resistant Enterobacteriaceae
Author(s): Timothy L. Wiemken, Robert R. Kelley, Ruth M. Carrico, Laura E. Binford, Brian E. Guinn, William A. Mattingly, and others
Source: American Journal of Infection Control Vol. 43 Issue 4 p380-382 February 5, 2015
DOC ID: 01

Efficacy and Safety of a Novel Skin Cleansing Formulation Versus Chlorhexidine Gluconate
Author(s): Paulson DS, Topp R, Boykin RE, Schultz G, Yang Q.
American Journal of Infection Control, Vol 46, Issue 11, p1262-1265, June 5, 2018

Author(s): Lisa Pinner, RN, MSN, CNS, CPON, BMTCN, Rachel Frisch, BSN, BMTCN, Jenna Kruger, MPH, CPHQ, and Lianna Marks, MD
Source: Lucile Packard Children’s Hospital (Stanford Health)
DOC ID: CLABSI.46

Author(s): George A Turini III M.D, MSc., Joseph F. Renzulli II M.D.
Source: Health – Doctors Medical Center of Modesto, 2020
DOC ID: CAUTI/CLABSI.12

CLABSI Reduction Seen with Multifactorial Nurse Initiative
Author(s): John Muir Health, CA
Source: ANCC Magnet Association, Fall Session, 2017
DOC ID: CLABSI.18
Institutional Clinical Studies: Event/Location
CAUTI/UTI (Catheter Acquired Urinary Tract Infection): Institutional Studies

Preventing Chronic Urinary Tract Infections From Urine and Fecal Incontinence: The Impact of Theraworx
Author(s): Jacque Whitley RN, Mariah Minor RN, Kate Loudon RN
Source: Peterson Healthcare, Peoria IL,

Author(s): Kimberly Parnell Burnett, MSN, Deborah Erickson, MSN, Ann Hunt, MSN, Lynn Beaulieu, MSN, Peggy Bobo, ADN, Penny Shute, BSN, MPH, Augusta, GA
Source: Journal of Emerg Nursing, 36(6) November 2010

Can’t Attribute UTI TO Insertion: Utilizing Data to Prevent CAUTI
Author(s): Smith, N.C., Granich, M., Lien, H., Schipper, A. University of Washington Medical Center, Seattle, WA
Source: UW Medicine University of Washington Medical Center

Equipping Clinicians with Advanced Care Options Leads to Reduction in UTI: Theraworx Works Wonders
Source: Meadowview Health and Rehab Center, AHCA Spring Session, 2017

Author(s): Jessica McClusky, MSN, RN, CPN, CIC Grand Rapids, Michigan
Source: Spectrum Health Helen Devos Children’s Hospital

The Theraworx Silver First Protocol: Impact on CAUTIs
Author(s): Christine M. Tusoch, RN, BSN, CIC (1); Kimberly A. Kovacic, RN (1); Timothy L. Wiemken PhD, MPH, CIC (2); 1. Euclid Hospital, Cleveland OH; 2. University of Louisville, Louisville, KY)
Source: Cleveland Clinic

Targeting Zero: One Hospital’s Journey to Reduce CAUTI
Author(s): Roser L, Piercy EC, Altpeter, T.
Source: Journ. Of Nurs Mgt 18-20 Dec 2014

Effects of Education and Improved Foley Catheter Care on Nurse’s Knowledge and CAUTI
Author(s): Walters G, Lee J, Riddle L
Source: First Health of the Carolinas

Source: Journal of Clinical and Medical Investigation. Vol 2(2): 1-3
CLABSI (Central Line Blood Stream Infection): Institutional Studies

A Patient-Centered Approach to Bathing Adherence in CLABSI in APHON
Author(s): Amanda Lucas MS, FNP, RN, CIC, Michelle DeBono RN, Katherine Eng RN, PNP, Ashley Ramirez MS, RN, CPNP-AC, Yves Valdez RN, MSN, CPHON, & Nancy Noonan MS, RN, PCNS-BC, BMTCN
Source: UCSF Health Improvement Symposium 2023

CLABSI Reduction Seen with Multifactorial Nurse Initiative
Author(s): John Muir Health, CA
Source: ANCC Magnet Association, Fall Session, 2017

Zero CAUTI, Zero CLABSI: Evaluating the Evidence-based Effectiveness of a Silver, pH Acidic, Multimodal Skin Decolonizing Wipe to Reduce Catheter Associated Urinary Tract Infection and Central Line Blood Stream Infections in the ICU Setting: A Retrospective Review
Author(s): Asif Saiyed, MBA, CIC, Director of Infection Prevention
Source: Tenet Health – Doctors Medical Center of Modesto, 2020

Journal of Critical Care Nursing: Change has arrived: antimicrobial bathing and CLABSI
Author(s): Sung P, Virgallito M, Murphy T, Boghossian R, Young R.
Source: Journal of Critical Care Nursing, April 2020
Source: USC Verdugo Hills Hospital

Source: St Jude Children’s Hospital
Author(s): Margie K, Qudeimat A, Browne E, Keerthi D, Sunkara A, Kang G, et al.
Source: Journal of Pediatric Oncology Nursing, 2020
Clostridium Difficile (CDI): Institutional Studies

Reducing the Incidence of Clostridium Difficile Infections, Antibiotics and Costs in a Long-Term Care Setting–A Surveillance Experience
Author(s): Susan M Johnston, BSN, CIC
Source: Levindale Lifebridge Health Center
Children’s Hospitals Studies

Effectiveness of Bath Wipes After Hematopoietic Cell Transplantation: A Randomized Trial
Source: St Jude Children’s Hospital
Author(s): Margie K, Qudeimat A, Browne E, Keerthi D, Sunkara A, Kang G, et al.
Source: Journal of Pediatric Oncology Nursing, 2020
Alternate Site Studies

Author(s): Jacque Whitley RN, Mariah Minor RN, Kate Loudon RN
Source: Peterson Healthcare, Peoria IL

Equipping Clinicians with Advanced Care Options Leads to Reduction in UTI: Theraworx Works Wonders
Source: Meadowview Health and Rehab Center
Source: AHCA Spring Session, 2017

Successful Healing of IAD When Traditional Barriers Fail Using an Innovative Topical Formulation
Author(s): Diana Gallagher MS, RN, CWOCN, CFCN, Janalynn Miller FNP-C, GNP, CWCN-AP
Source: Symposium for Advanced Wound Care Fall 2018
Organisms, Wound & Skin
Organism Efficacy Studies

Microbial Test Results: Microbial Testing Executive Summary
Author(s): Timothy L. Wiemken, Robert R. Kelley, Ruth M. Carrico, Laura E. Binford, Brian E. Guinn, William A. Mattingly, and others
Source: Microbiological Consultants, Apptec Laboratories, St. John’s Research Institute

Efficacy of a Novel Skin Antiseptic Against Carbapenem-Resistant Enterobacteriaceae
Author(s):Timothy L. Wiemken, Robert R. Kelley, Ruth M. Carrico, Laura E. Binford, Brian E. Guinn, William A. Mattingly, and others
Source: American Journ of Infection Control, Vol. 43 Issue 4 p380–382. Published Online February 5, 2015

Efficacy and Safety of a Novel Skin Cleansing Formulation Versus Chlorhexidine Gluconate
Author(s): Paulson DS, Topp R, Boykin RE, Schultz G, Yang Q
Source: R. Journal of Wound Ostomy & Continence Nursing, May 2020

Source: Bioscience Laboratories, Inc.

Source: St. John’s Medical Research Institute

Source: St. John’s Research Center

Source: Journal of Clinical and Medical Investigations, October 2020
DOC ID: 01

Activity of a Novel, Multimodal, Surfactant-based Skin Cleanser on Coronaviruses, In-vitro
Source: Clinical and Medical Investigations ISSN:2398-5763

Source: Nelson Labs
Wound And Skin Integrity Studies

Effect of an Innovative pH Lowering Wound Therapeutic on MMP Levels and Bacterial Biofilm Colonization of Chronic Non-healing Wounds
Author(s): William Marston, Gregory Schultz, Zachary Gortler, Kurt Schultz, Soo Jung Seo, Daniel Gibson, Haley Engelken
Source: Symposium on Advanced Wound Care, Fall 2019

Harnessing the Microbiome to Rapidly Resolve Peristomal Skin Complications
Author(s): Gallagher D, Juergens J.
Source: Symposium on Advanced Wound Care, Spring 2019

Successful Healing of IAD When Traditional Barriers Fail Using an Innovative Topical Formulation
Author(s): Gallagher D, Miller J.
Source: Symposium on Advanced Wound Care, Fall 2018
Clinical Data Brochure
Reference Documents

The Skin Barrier as an Innate Immune Element
Source: Immunopath (2007) 29:3-14

The How, Why, and Clinical Importance of Stratum Corneum Acidification
Source: Experimental Dermatology Journ March 2017

pH Directly Regulates Permeability Barrier Homeostasis and Stratum Corneum Cohesion/Integrity
Source: Journ Invest Dematol, August 2003, issue: 121(12), p: 345-53

Safety

Source: Independent Testing by BioScience Laboratories, Phoenix, AZ

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